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. 2018 Jun 1;13:3263–3278. doi: 10.2147/IJN.S166021

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© 2018 Lee et al. This work is published and licensed by Dove Medical Press Limited

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Characterization of RIPL-NLC.

Notes: (A) Time-dependency of the thiol-maleimide reaction. (B) Comparison of the calculated FALT of NLC and RIPL-NLC. (C) TEM images of DTX-NLC and DTX-RIPL-NLC. (D) DSC thermograms of DTX, Precirol^® ATO 5, DTX-NLC, and DTX-RIPL-NLC. Data are mean ± SD (n=3).

Abbreviations: DSC, differential scanning calorimetry; DTX-NLC, DTX-loaded nanostructured lipid carrier; DTX-RIPL-NLC, docetaxel-loaded RIPL peptide-conjugated nanostructured lipid carrier; FALT, fixed aqueous layer thickness; NLC, nanostructured lipid carrier; RIPL-NLC, RIPL peptide-conjugated nanostructured lipid carrier; TEM, transmission electron microscopy.