Figure 6.

Confocal microscopic images with orthogonal views of SKOV3 and PC-3 cells.

Notes: Cells incubated with DiI-RIPL-NLC for 0 (immediately after the treatment), 1, 2, and 4 h. The nucleus was stained with DAPI for blue fluorescence and merged with red fluorescence of DiI distributed in the cytoplasm. The positions of the section plane are indicated by colored lines; XY plane (blue), XZ plane (green), YZ plane (red). The white scale bar represents 20 µm.

Abbreviations: DAPI, 4′,6-diamino-2-phenylindole; DiI, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; DiI-Sol, DiI solution; DiI-NLC, DiI-loaded nanostructured lipid carrier; DiI-RIPL-NLC, DiI-loaded RIPL peptide-conjugated nanostructured lipid carrier; Hpn, hepsin.