Table 2.
Connectivity analysis with CONN toolbox comparing MRI-1 and MRI-2.
| ROI | MNI coordinates | ROI | MNI coordinates | T | P value | |
|---|---|---|---|---|---|---|
| Angular_L | (−44; −61; 36) | – | Angular_R | (46; −60; 39) | 4.57 | <0.01 |
| Angular_R | (46; −60; 39) | – | Angular_L | (−44; −61; 36) | 3.96 | 0.04 |
| Calcarine_R | (16; −73; 9) | – | Calcarine_L | (−7; −79; 6) | 4.02 | 0.03 |
| Caudate_L | (−11; 11; 9) | – | Caudate_R | (15; 12; 9) | 4.59 | 0.01 |
| Caudate_R | (15; 12; 9) | – | Caudate_L | (−11; 11; 9) | 5.03 | <0.01 |
| Cingulum_Ant_L | (−4; 35; 14) | – | Cingulum_Ant_R | (8; 37;16) | 4.19 | 0.02 |
| Cingulum_Ant_R | (8; 37;16) | – | Cingulum_Ant_L | (−4; 35; 14) | 4.04 | 0.03 |
| Cingulum_Mid_L | (−5; −15; 42) | – | Cingulum_Mid_R | (8; −9; 40) | 4.60 | 0.01 |
| Cingulum_Mid_R | (8; −9; 40) | – | Cingulum_Mid_L | (−5; −15; 42) | 4.60 | 0.01 |
| Cingulum_Post_L | (−5; −43; 25) | – | Cingulum_Post_R | (7; −42; 22) | 5.90 | <0.01 |
| Cingulum_Post_R | (7; −42; 22) | – | Cingulum_Post_L | (−5; −43; 25) | 5.69 | <0.01 |
| Frontal_Inf_Tri_L | (−46; 30; 14) | – | Frontal_Inf_Tri_R | (50; 30; 14) | 4.69 | 0.01 |
| Frontal_Inf_Tri_R | (50; 30; 14) | – | Frontal_Inf_Tri_L | (−46; 30; 14) | 3.84 | <0.05 |
| Frontal_Mid_L | (−33; 33; 35) | – | Frontal_Mid_R | (38; 33; 34) | 4.65 | 0.01 |
| Frontal_Mid_R | (38; 33; 34) | – | Frontal_Mid_L | (−33; 33; 35) | 4.62 | 0.01 |
| Frontal_Mid_Orb_R | (33; 53; −11) | – | Frontal_Sup_R | (22; 31; 44) | 3.98 | 0.03 |
| Frontal_Sup_R | (22; 31; 44) | – | Frontal_Mid_Orb_R | (33; 53; −11) | 4.00 | 0.03 |
| Frontal_Sup_Medial_L | (−5; 49; 31) | – | Frontal_Med_Orb_L | (−5; 54; −7) | 4.11 | 0.03 |
| Insula_L | (−35; 7; 3) | – | Insula_R | (39; 6; 2) | 4.33 | 0.01 |
| Insula_R | (39; 6; 2) | – | Insula_L | (−35; 7; 3) | 4.41 | 0.01 |
| Occipital_Mid_R | (37; −80; 19) | – | Occipital_Mid_L | (−32; −81; 16) | 5.76 | <0.01 |
| Parietal_Inf_R | (46; −46; 50) | – | Parietal_Inf_L | (−43; 46; 47) | 3.89 | 0.04 |
| Postcentral_L | (−42; −23; 49) | – | Postcentral_R | (41; −25; 53) | 8.17 | <0.01 |
| Postcentral_R | (41; −25; 53) | – | Postcentral_L | (−42; −23; 49) | 7.00 | <0.01 |
| Precuneus_L | (−7; −56; 48) | – | Precuneus_R | (10; −56; 44) | 5.87 | <0.01 |
| Precuneus_R | (10; −56; 44) | – | Precuneus_L | (−7; −56; 48) | 5.34 | <0.01 |
| Putamen_L | (−24; 4; 2) | – | Putamen_R | (28; 5; 2) | 6.01 | <0.01 |
| Putamen_R | (28; 5; 2) | – | Putamen_L | (−24; 4; 2) | 6.00 | <0.01 |
| SupraMarginal_L | (−56; − 34; 30) | – | SupraMarginal_R | (58; −32; 34) | 5.27 | <0.01 |
| SupraMarginal_R | (58; −32; 34) | – | SupraMarginal_L | (−56; − 34; 30) | 4.23 | 0.02 |
| Thalamus_L | (−11; −18; 8) | – | Thalamus_R | (13; −18; 8) | 5.30 | <0.01 |
| Thalamus_R | (13; −18; 8) | – | Thalamus_L | (−11; −18; 8) | 5.48 | <0.01 |
Patients were scanned successively before surgery (MRI-1) and immediately after surgery, within 36 h following surgery (MRI-2). All reported P values are found significant with an analysis-level FDR correction for the hypothesis of a decrease in functional connectivity from MRI-1 to MRI-2. Names of the ROIs refer to the AAL atlas. Abbreviations: L: left; R: right.