Table 1. Retrovirus integration sites identified by inverse PCR.
Mouse no. | Gene name | Genome position | Integration site | Gene description |
---|---|---|---|---|
1 | Ly6e | chr15(qD3) | 20 kb up | Lymphocyte antigen 6 complex, locus E |
Fgd2 | chr17(qA3,3) | 15 kb down | FYVE, RhoGEF, and PH domain containing 2 | |
H2-Eb2a | chr17(qB1) | Intron 1 | Histocompatibility 2, class II antigen E beta2 | |
Fn1 | chr1(qC3) | 200 kb down | Fibronectin 1 | |
Acvrl1 | chr15(qF1) | 10 kb down | Activin A receptor, type II–like 1 | |
Rab37 | chr11(qE2) | Intron 1 | RAB37, member RAS oncogene family | |
Pitpnc1 | chr11(qE1) | Intron 1 | Phosphatidylinositol transfer protein, cytoplasmic 1 | |
Zfp541 | chr7(qA2) | 15 kb up | Zinc-finger protein 541 | |
Numb | chr12(qD1) | 15 kb up | Numb homologue (Drosophila) | |
Irf8 | chr8(qE1) | 50 kb down | Interferon regulatory factor 8 | |
Rnf220a | chr4(qD1) | Intron 2 | Ring-finger protein 220 | |
Fcnb | chr2(qA3) | 10 kb up | Ficolin B | |
Padi2 | chr4(qD3) | 1 kb up | Peptidyl arginine deiminase, type II | |
Kctd12 | chr14(qE2,3) | 100 kb down | Potassium channel tetramerization domain containing 12 | |
Myb | chr10(qA3) | Intron 9 | Myeloblastosis oncogene | |
Hhexa | chr19(qC2) | 50 kb down | Hematopoietically expressed homeobox | |
2 | Arpc3 | chr5(qF) | Intron 2 | Actin-related protein 2/3 complex, subunit 3 |
Setbp1 | chr18(qE3) | 200 kb up | SET-binding protein 1 | |
M1ap | chr(qC3) | Exon 1 (5′ UTR) | Meiosis 1–associated protein | |
Ift81 | chr5(qF) | 10 kb up | Intraflagellar transport 81 | |
3 | Cmb1 | chr15(qB2) | 0.2 kb up | Carboxymethylenebutenolidase-like (Pseudomonas) |
Gsn | chr2(qB) | 10 kb up | Gelsolin | |
Qars | chr9(qF2) | Intron 1 | Glutaminyl-tRNA synthetase | |
Rbbp6 | chr7(qF2) | 20 kb up | Retinoblastoma-binding protein 6 | |
Prdm16 | chr4(qE2) | Intron 1 | PR domain containing 16 | |
Mkln1 | chr6(qA3,3) | 200 kb up | Muskelin 1, intracellular mediator containing kelch motifs | |
Fhad1 | chr4(qE1) | Intron 13 | Forkhead-associated phosphopeptide binding domain 1 | |
Rassf2 | chr2(qF2) | Intron 1 | Ras association (RalGDS/AF-6) domain family member 2 | |
Neurl1b | chr17(qA3,3) | 20 kb up | Neuralized E3 ubiquitin protein ligase 1B | |
Rnf220a | chr4(qD1) | Intron 2 | Ring finger protein 220 | |
EV1 | chr12(qF1) | Intron 1 | Ena-vasodilator stimulated phosphoprotein | |
Ubash3a | chr17(qA3,3) | Intron 6 | Ubiquitin associated and SH3 domain containing, A | |
Pcbp1 | chr6(qD1) | 20 kb down | Poly(rC) binding protein 1 | |
4 | Fggy | chr4(qC5) | 200 kb up | FGGY carbohydrate kinase domain containing |
Adgre5 | chr8(qC2) | Intron 1 | Adhesion G protein–coupled receptor E5 | |
Smim19 | chr8(qA2) | Exon 5 (3′ UTR) | Small integral membrane protein 19 | |
Igch | chr9(qC) | Intron 13 | IQ motif containing H | |
Pim1 | chr17(qA3,3) | 1 kb up | Proviral integration site 1 | |
Serpina3j | chr12(qE) | Intron 2 | Serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J | |
Katnal1 | chr5(qG3) | 50 kb up | Katanin p60 subunit A–like 1 | |
H2-Eb2a | chr17(qB1) | Intron 1 | Histocompatibility 2, class II antigen E beta2 | |
5 | Rere | chr4(qE2) | Intron 11 | Arginine glutamic acid dipeptide (RE) repeats |
B3gnt2 | chr11(qA3,2) | Intron 1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | |
Casp8 | chr1(qC1,3) | Intron 1 | Caspase-8 | |
Hhexa | chr19(qC2) | 20 kb down | Hematopoietically expressed homeobox | |
Fam76a | chr4(qD2,3) | 20 kb up | Family with sequence similarity 76, member A | |
Rhoh | chr5(qC3,1) | 50 kb down | ras homologue family member H | |
Xxylt1 | chr16(qB2) | Intron 3 | Xyloside xylosyltranserase 1 | |
6 | Tmprss4 | chr9(qA5,2) | Intron 1 | Transmembrane protease, serine 4 |
Rras2 | chr7(qF1) | 50 kb up | Related RAS viral (r-ras) oncogene 2 | |
Adrbk2 | chr5(qF) | Intron 1 | Adrenergic receptor kinase, beta 2 | |
Stx6 | chr1(G3) | 5 kb up | Syntaxin 6 | |
Ets2 | chr16(qC4) | 100 kb down | E26 avian leukemia oncogene 2, 3′ domain | |
Tmprss4 | chr9(qA5,2) | Intron 1 | Transmembrane protease, serine 4 | |
Pla2g15 | chr8(qD3) | Intron 1 | Phospholipase A2, group XV | |
Zmiz1 | chr14(qA3) | 50 kb up | Zinc finger, MIZ-type containing 1 | |
Brip1os | chr11(qC) | Intron 1 | BRCA1-interacting protein C-terminal helicase 1, opposite strand | |
Ephb2 | chr4(qD3) | Exon 1 (5′ UTR) | Eph receptor B2 | |
Plin3 | chr17 | 1 kb up | Perilipin 3 |
Retroviral common integration site.