Table 1.
Study | Design (level of evidence) | Cases | Procedure | Infection rate | Surgical site infection associations |
---|---|---|---|---|---|
Harness et al28 | Retrospective, multicenter (III) | 2336 | CTR | Antibiotic prophylaxis vs control: SSI: 0.4% vs 0.7% (P = .354) DI: 0.1% vs 0.2% (P = 1) |
No association with sex, age, or DM |
Bykowski et al8 | Retrospective, single-center (III) | 6095 | CTR | Antibiotic prophylaxis vs control: 0.54% vs 0.26% (P > .05) |
Infection associated with tobacco, DM, and longer operative time Prophylactic antibiotic did not prevent SSI in males, tobacco users, or for those with longer operative times |
Tosti et al51 | Retrospective, multicenter (III) | 600 | CTR, DQR, TFR, and ME | Antibiotic prophylaxis vs control: 0.47% vs 0.77% (P = 1) |
No association with DM and tobacco |
Note. CTR = carpal tunnel release; SSI = surgical site infection; DI = deep infection; DM = diabetes mellitus; DQR = De Quervain release; TFR = trigger finger release; ME = mass excision.