Table 1.
Name of Disease Category, ICD-10 Code, and Number of Individual Studies Investigating the Association Between Adult ADHD and Somatic Disease.
| Diagnosis | ICD-10 code | Number of individual studies | Association and quality of evidencea |
|---|---|---|---|
| In general | 4 | ||
| Resistance to thyroid hormone | E07.8 | 1 | Association (3) |
| Hypothyroidism | E00-E03 | 1 | Association (3) |
| Diabetes | E10-E14 | 3 | No/negative association (3) |
| Nutritional diseases | |||
| Obesity | E66 | 22 | Association (1) |
| Metabolic disorders | E70-E90 | ||
| In general | 1 | Association (3) | |
| Albinism | E70.3 | 1 | Association (3) |
| Maple syrup urine disease | E71.0 | 1 | Association (3) |
| Diseases of the nervous system | |||
| Restless legs | G25 | 6 | Association (3) |
| Dementia with Lewy bodies | G31.83 | 1 | Association (3) |
| Epilepsy | G40 | 3 | Association (3) |
| Migraine | G43 | 2 | Association (2) |
| Sleep disorders | G47 | 25 | Association (1) |
| Myotonic dystrophy | G71.1 | 2 | Association (3) |
| Chronic fatigue syndrome | G93.3 | 2 | Association (3) |
| Diseases of the circulatory system | Chapter IX | 4 | No association (2) |
| Allergic diseases | |||
| In general | 2 | Association (3) | |
| Allergic rhinitis | J30 | 1 | Association (3) |
| Respiratory disorders | Chapter X | ||
| In general | 2 | Association (3) | |
| Asthma | J46 | 7 | Association (1) |
| Diseases of the digestive system | Chapter K | ||
| In general | 1 | Association (3) | |
| Irritable bowel syndrome | K58 | 2 | Association?b (3) |
| Celiac disease | K90.9 | 3 | Association (2) |
| Skin disorders | Chapter XII | ||
| In general | 1 | No association (3) | |
| Atopic dermatitis | L20 | 1 | Association (3) |
| Alopecia areata | L63 | 1 | No association (3) |
| Acne (ICD-10: L70) | L70 | 1 | Association (3) |
| Musculoskeletal disorders | Chapter XIII | ||
| In general | 3 | Association (3) | |
| Rheumatoid arthritis | M05-M06 | 1 | No association (3) |
| Systemic lupus erythematosus | M32 | 2 | Association (3) |
| Fibromyalgia | M79.7 | 2 | Association (3) |
| Calvé-Legg-Perthes | M91.1 | 1 | Association (3) |
| Congenital syndromes and anomalies | Chapter XVII | 12 | |
| Symptoms/signs involving the urinary system | R30-R39 | ||
| In general | 1 | No association (3) | |
| Enuresis | R32 | 3 | Association?b (3) |
Note. ICD-10 = International Classification of Diseases; Conditions classified in (1) or ( 2) in bold.
a
The reported studies were classified into conditions (1) where the association between ADHD and the somatic disease is well established, (2) where there is tentative evidence for an association, and (3) where evidence is still too weak to make conclusions.
b
Conflicting evidence. One study shows no association, another study/studies show association. See text for more information.