Clinical signs	D1-0 h	D1-2 h	D1-4 h	D2	D3	D4	D5	D6	D7 etc. up to 15
Bodyweight (g)	150	–	–	145	150	152	155	158
Skin and fur: stains (0–1)	0	0	0	0	0	0	0	0	0
Skin and fur: pale (0–3)	0	0	0	0	0	0	0	0	0
Involuntary clonic movements (0–3)	0	0	0	0	0	0	0	0	0
Involuntary tonic movements (0–3)	0	0	0	0	0	0	0	0	0
Tremors (0–3)	0	0	0	0	0	0	0	0	0
Salivation (0–3)	0	1	0	0	0	0	0	0	0
Lacrimation (0–1)	0	1	0	0	0	0	0	0	0
Diarrhoea (0–1)	0	0	0	0	0	0	0	0	0
Vocalisations (0–1)	0	0	0	0	0	0	0	0	0
Stereotypy: excessive grooming (0–1)	0	0	0	0	0	0	0	0	0
Stereotypy: repetitive circling (0–1)	0	0	0	0	0	0	0	0	0
Bizarre behaviour: self-mutilation (0–1)	0	0	0	0	0	0	0	0	0
CNS: lethargy (0–3)	0	2	2	0	0	0	0	0	0
CNS: convulsions (0–3)	0	0	0	0	0	0	0	0	0
Posture: hunched posture (0–1)	0	1	1	0	0	0	0	1	1
Posture: rearing (0–1)	0	0	0	0	0	0	0	0	0
Posture: ventro-lateral recumbency (0–1)	0	0	0	0	0	0	0	0	0
Gait abnormalities: uncoordinated movements (0–3)	0	1	1	0	0	0	0	0	0
Piloerection (0–1)	0	1	1	0	0	0	0	0	0
Ptosis (palpebral closure) (0–3)	0	1	1	0	0	0	0	0	0
Respiratory abnormalities: laboured respiration (0–3)	0	0	0	0	0	0	0	0	0
Respiratory abnormalities: Rales (0–3)	0	1	1	0	0	0	0	0	0