Fig. 1.

Results of the local gyrification index analysis comparing healthy subjects to DD in the left hemisphere. In the top left the figure shows clusters of regions having a statistically significant difference in correlation between lGI and age compared to TDC. Clusters are overlaid to an inflated brain volume shown on a lateral view. The map is -log10(P), where P is the significance, so a Min of 2 will display all vertices with P < 0.01 and a Max of 5 will show vertices of P < 0.0001 as the same color. Scatter plots of three representative clusters are also shown. Age is reported on the x-axis, whereas lGI values are represented on the y-axis for healthy (blue) and DD (red) subjects. Spearman r and P values for the age and lGI correlation are also reported and marked with “*” once statistically significant (P < 0.05). In dyslexic children there was a lack of inverse correlation between age and lGI: lGI seems not to reduce with age as observed and described in literature. The same clusters showed a statistically significant increased lGI in DD compared to healthy subjects. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)