Table 1.
Study | Year | Country | Diseases | Case no | Stage | Sample | Assay | Cut-off value | HR | Follow-up (months) | Type of miR-17 detection |
Chen et al37 | 2012 | China | HCC | 120 | I–IV | Tissue | qRT-PCR | Median | RR | 46 | miR-17–5p |
Qun et al27 | 2013 | China | Lung cancer | 221 | I–IV | Tissue | qRT-PCR | Median | Given | 50 | miR-17 |
Li et al41 | 2014 | China | Osteosarcoma | 117 | I–III | Tissue | qRT-PCR | Median | Given | 44 | miR-17 |
Lu et al35 | 2012 | China | Glioma | 108 | I–IV | Tissue | qRT-PCR | Mean | RR | 60 | miR-17 |
Xi et al42 | 2015 | China | T-cell lymphoblastic lymphoma | 57 | III, IV | Tissue | qRT-PCR | Median | Given | Up to 13 years | miR-17 |
Yu et al40 | 2012 | China | Colon cancer | 48 | I–IV | Tissue | qRT-PCR | Median | Given | 5–66 | miR-17 |
Manuel et al39 | 2011 | Spain | Gastrointestinal cancer | 38 | I–IV | Tissue | qRT-PCR | Mean | Given | 38 | miR-17 |
Robaina et al38 | 2016 | Brazil | Burkitt lymphoma | 41 | I–IV | Tissue | ISH | Median | Given | 69 | miR-17 |
Xu et al36 | 2014 | China | Oesophageal squamous cell carcinoma | 105 | I–IV | Tissue | qRT-PCR | Mean | Given | 52 | miR-17 |
Jun et al26 | 2010 | Japan | Pancreatic cancer | 80 | I–IV | Tissue | qRT-PCR | Median | Given | 60 | miR-17–5p |
Wang et al43 | 2011 | China | Gastric cancer | 65 | I–IV | Serum | qRT-PCR | Median | Given | 36 | miR-17–5p |
Zheng et al34 | 2013 | China | HCC | 96 | I–IV | Serum | qRT-PCR | Median | Given | NG | miR-17–5p |
HCC, hepatocellular carcinoma; ISH, in situ hybridisation; miR-17, microRNA-17; NG, not given; OS, overall survival; qRT-PCR, quantitative real-time PCR; RR, risk ratio.