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. 2018 May 3;8(5):e020777. doi: 10.1136/bmjopen-2017-020777

Table 2b.

Least square means and 95% CIsfor left ventricular structural indices according to categories of alcohol consumption

N LS means* (95% CI) of alcohol consumption categories P values
Non-drinkers ≥0.5 and ≤3 drinks per week >3 and ≤7 drinks per week >7 drinks per week Linear Quadratic
LV mass (g)
 Men 551 157.0 (146.8 to 167.2) 158.6 (153.1 to 164.0) 169.5 (160.7 to 178.2) 182.1 (164.6 to 199.7) <0.01 0.92
 Women 578 151.6 (142.0 to 161.2) 159.5 (154.1 to 164.9) 169.3 (160.6 to 177.9) 180.0 (162.7 to 197.3) <0.01 0.13
LV mass per BSA (g/m2)
 Men 550 76.8 (71.5 to 82.1) 78.6 (75.8 to 81.4) 83.0 (78.5 to 87.5) 91.4 (82.3 to 100.4) <0.01 0.67
 Women 577 86.1 (80.4 to 91.8) 90.4 (87.2 to 93.6) 95.5 (90.4 to 100.6) 102.6 (92.4 to 112.8) <0.01 0.02
LV end-diastolic diameter (mm)
 Men 548 50.7 (49.5 to 51.9) 50.9 (50.3 to 51.5) 51.0 (50.0 to 52.0) 52.1 (50.0 to 54.2) 0.03 0.23
 Women 577 49.4 (48.3 to 50.5) 50.4 (49.8 to 51.1) 51.4 (50.4 to 52.4) 52.5 (50.5 to 54.6) 0.07 0.31
LV end-systolic diameter (mm)
 Men 548 32.3 (31.2 to 33.4) 32.4 (31.8 to 33.0) 32.4 (31.5 to 33.4) 33.9 (31.9 to 35.8) 0.17 0.29
 Women 577 31.1 (30.1 to 32.1) 32.2 (31.6 to 32.8) 32.7 (31.8 to 33.7) 34.6 (32.8 to 36.5) <0.01 0.48
Relative wall thickness (cm)
 Men 551 0.25 (0.24 to 0.26) 0.26 (0.25 to 0.26) 0.27 (0.27 to 0.27) 0.27 (0.25 to 0.28) 0.07 0.96
 Women 578 0.26 (0.25 to 0.27) 0.26 (0.26 to 0.27) 0.26 (0.26 to 0.27) 0.27 (0.26 to 0.28) 0.47 0.31

*Means are adjusted for age, marital status and education, smoking, physical activity and body mass index.

BSA, body surface area; e’, peak early diastolic mitral annular velocity; LV, left ventricular; RS’, peak tricuspid annular systolic velocity, S’, peak systolic mitral annular velocity; TAPSE, tricuspid annular plane systolic excursion.