Table 4.

Differential diagnoses: other diseases that should be differentiated from EGE

EGE differential diagnoses

– Intestinal parasites: infection with Ancylostoma, Anisakis, Ascaris, Strongyloides, Toxocara, Trichiura, Capillaria, Basidiobolomycosis, and Trichinella can cause gastrointestinal symptoms and peripheral eosinophilia; infection with the dog hookworm, Ancylostoma caninum, can mimic EGE clinically and pathologically with eosinophilic infiltration of the gut wall and ascites

– Malignancy: lymphoma, gastric cancer, and colon cancer

– Inflammatory bowel disease: Crohn's disease associated with peripheral eosinophilia and/or an eosinophil-rich tissue infiltrate (rare)

– Hypereosinophilic syndrome

– Polyarteritis nodosa

– Eosinophilic granulomatosis with polyangiitis

– Eosinophilic granuloma (Langerhans cell histiocytosis)