Table 1.

Clinical, endoscopic, laboratory, radiological, and histological features of CD and ITB

Features	CD	ITB
Clinical
Perianal disease	Common	Rare
Blood in stool	Presence	Rare
Endoscopy
Distribution	≥4 segments	<4 segments
Ulcer appearance	Longitudinal	Transverse
Patulous ileocecal valve	Rare	Common
T-SPOT.TB	Negative	Positive (higher counts)
Active pulmonary TB (chest X-ray/CT scan)	No	Presence
CT enterography
Multisegmental involvement	Common	Less common
Sigmoid colon/rectum involvement	Common	Less common
Asymmetric distribution	Common	Less common
Comb sign	Common	Less common
Fibrofatty change	Common	Less common
Biopsy histology
Focal chronic inflammation	Common	Less common
Granuloma	Solitary, <400 µm, noncaseating	Merged, ≥400 µm, caseating