Skip to main content
. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Mamm Genome. 2017 Dec 1;29(1-2):128–140. doi: 10.1007/s00335-017-9726-3

Figure 3. Functional relationships among transcripts in the liver transcriptional coexpression module associated with alcohol consumption (Module 86).

Figure 3

Each of the transcripts in the coexpression module is circled in blue. The ⨁ and ⊝ signs indicate the effects of the transcript products on the activity of the indicated pathway. The module eigengene is positively correlated with the phenotype of alcohol consumption across the HXB/BXH RI strains, as indicated by the arrow on the left. The correlations among the transcripts are indicated in Figure 2. ↑BBB = increase in permeability of the blood-brain barrier; PreK = prekallikrein; K = kallikrein; BK = bradykinin; BK1R and BK2R = bradykinin 1 and 2 receptors, respectively.