. Author manuscript; available in PMC: 2018 Jun 5.

Published in final edited form as: Biochem J. 2018 Jan 11;475(1):273–288. doi: 10.1042/BCJ20170702

Table 3.

Thermal denaturation parameters

Enzyme	T_m (ºC)	ΔH_VH (kcal·mol⁻¹)	ΔT_m (ºC)^a
OXA-23	60.4	180 ±16	-
OXA-239	56.0	240 ± 30	−4.4
OXA-23 S109L	62.0	260 ± 59	+1.6
OXA-23 D222N	59.0	164 ± 15	−1.4
OXA-23 P225S	57.2	204 ± 20	−3.2
OXA-23 D222N/P225S	55.2	226 ± 13	−5.2

ΔT_m = T_variant-T_WT are relative to OXA-23