. 2018 Jun 5;13(6):e0197071. doi: 10.1371/journal.pone.0197071

Table 2. Biometric parameters and consumption of feed and water of non-diabetic (ND) mice treated with water (D-Control), metformin (D-Metformin), and Apis mellifera bee tea (D-AmT) for 21 days.

Parameters	ND-Control	D-Control	D-Metformin	D-AmT
Δ body weight _(%)	5.9 ± 0.2^a	-13.7 ± 0.4^b	-9.8 ± 0.3^c	-13.8 ± 0.3^b
Feed consumption _{(g/day/animal)}	4.2 ± 0.5^a	3.3 ± 0,4^a	3.9 ± 0,7^a	3.9 ± 0,4^a
Water intake _{(mL/day/animal)}	2.7 ± 0.3^a	8.3 ± 0.7^b	2.1 ± 0.4^a	1.8 ± 0.4ª
Subcutaneous WAT _{(g/100 g of BW)}	0.29 ± 0.07^a	0.08 ± 0.02^b	0.18 ± 0.05^a	0.23 ± 0.06^a
Mesenteric WAT _{(g/100 g of BW)}	0.68 ± 0.15^a	1.12 ± 0.27^a	0.96± 0.26^a	1.23 ± 0.31^a
Epididymal WAT _{(g/100 g of BW)}	2.99 ± 0.30^a	2.09 ± 0.41^a	1.63 ± 0.49^a	1.97 ± 0.26^a
Retroperitoneal WAT _{(g/100 g of BW)}	0.75 ± 0.11^a	0.71 ± 0.08^a	0.78 ± 0.20^a	0.98 ± 0.22^a

Δ, body weight variation between the beginning and end of the 21-day treatment expressed in %; WAT, white adipose tissue. Different letters indicate P<0.05 between groups.