. 2018 Jun 5;13(6):e0198478. doi: 10.1371/journal.pone.0198478

Table 1. CC₅₀ and EC₅₀ values of the reference compound 2 and the control drug raltegravir (RAL) on human CD4⁺ T lymphocytes.

Compound	NL 4.3 WT EC₅₀(nM)	AD8 WT EC₅₀(nM)	Q148H, G140S EC₅₀(nM)	Y143R EC₅₀ (nM)	CC₅₀ (nM)	SI
2	13±3	11±1	9±2	8±3	810±20	62
RAL	3±2	2±3	800±12	460±10	n.a	n.a

SI = Selectivity Index. EC₅₀ = Half maximal effective concentration. CC₅₀ = Half maximal cytotoxic concentration. Values represent mean±S.D of three independent experiments.

Table 1. CC50 and EC50 values of the reference compound 2 and the control drug raltegravir (RAL) on human CD4+ T lymphocytes.

Table 1. CC₅₀ and EC₅₀ values of the reference compound 2 and the control drug raltegravir (RAL) on human CD4⁺ T lymphocytes.