Table 5. Mean relative expression of candidate genes with clinicopathological variables.

	Characteristic	Age		Gender		Tumor site		TNM stage
		≤ 57	> 57	Male	Female	Colon	Rectum	I&II	III&IV
	% for 50 samples	44	56	52	48	48	52	57.7	34.6
	% for 20 samples	45	55	45	55	55	45	35	65
TERT°	Mean ±SEM	0.67 ±0.12	1.47 ±0.38	1.30 ±0.38	0.86±0.25	0.96± 0.23	1.4 ± 0.43	1.5±0.2	0.8±0.2
	P-value	0.05*		n.s		n.s		n.s
TRF1	Mean ±SEM	0.77 ±0.13	0.53 ±0.14	0.47 ±0.16	0.82 ±0.11	0.68 ± 0.09	0.57 ±0.16	0.79 ±0.25	0.52 ±0.07
	P-value	n.s		n.s		n.s		n.s
TRF2	Mean ±SEM	0.80±0.15	0.79±0.08	0.72±0.1	0.88±0.12	0.88±0.12	0.71±0.09	0.66±0.12	0.87±0.09
	P-value	n.s		n.s		n.s		n.s
POT1	Mean ±SEM	1.46 ±0.31	1.34 ±0.20	*1.47 ±0.14	1.31 ±0.31	1.30 ±0.25	1.46 ±0.18	1.40 ±0.44	1.39 ±0.16
	P-value	n.s		n.s		n.s		n.s
ATR	Mean ±SEM	1.33 ±0.14	*1.59 ±0.18	1.08 ±0.14	**2.04 ±0.20	**1.66 ± 0.17	1.28 ±0.16	1.5 ±0.19	*1.45 ±0.14
	P-value	n.s		0.009**		n.s		n.s
ATM	Mean ±SEM	0.81±0.17	0.81±0.12	0.67±0.14	0.93±0.15	1.09±0.18	*0.58±0.12	0.78±0.20	0.83±0.12
	P-value	n.s		n.s		0.029*		n.s
Chk1	Mean ±SEM	1.06 ±0.11	1.37 ±0.14	2.08 ±0.50	1.38 ±0.31	1.31 ± 0.33	*2.16 ±0.42	1.98 ±0.50	1.38 ±0.24
	P-value	n.s		n.s		n.s		n.s
Chk2	Mean ±SEM	1.40±0.11	0.90±0.21	1.30±0.29	1.09±0.12	0.96±0.08	1.54±0.35	1.26±0.35	1.14±0.13
	P-value	n.s		n.s		n.s		n.s

°hTERT clinical data analysis based on 50 samples, others gene on 20 samples of the 50.

* (pvalue < 0.05)

** (pvalue < 0.01)