Table 1. Main demographic and epidemiological model inputs to estimate the cost-effectiveness of an illustrative dog rabies vaccination programs in East Africa.
| Model Variable | Model Values | Source | |
|---|---|---|---|
| Urban | Rural | ||
| Human population | |||
| Total Human Population | 661,444 | 338,047 | [25] |
| Square kilometers (km2) | 220 | 1,792 | [25] |
| Human Population (per km2) | 3,007 | 189 | Calculateda |
| Human birth rate (per 1,000 pop) | 36.0 | 39.8 | [26] |
| Human life expectancy(yrs) | 58.5 | 58.5 | [27] |
| Life expectancy at age 10 yrs | 52.8 | 52.8 | [27] |
| Average age of death due to dog rabies (yrs) | 10 | 10 | [2] |
| Estimated annual human deaths from dog rabies at the beginning of the program | 20 | 10 | [1,2,20] |
| Dog population | |||
| Number of humans-per-dogb | 18.1 | 7.4 | [2, 20, 30] |
| Total Dog Population | 36,544 | 45,682 | Calculateda |
| Dog per km2 | 166 | 25.5 | Calculateda |
| Dog birth rate (per 1,000 dogs)c | 676 | 572 | [7,29] |
| Dog life expectancy, yearsd | 3 | 3 | [29] |
| Probability of clinical outcome (dogs) | 0.45 | 0.45 | [8] |
a Calculated using the RabiesEcon tool. Please see Supplemental material.
b The numbers of humans-per-dog for Blantyre were obtained from Gibson et al. [20]; the estimate for rural areas was based on Knobel et al.’s estimate for Africa [2].
c The urban dog birth rate was obtained from a dog population household survey in N’Djamena, Chad [7]. For the rural scenario, we used data from Machakos District, Kenya [28].
d Life expectancy at birth was 3.5 and 2.4 years for male and female dogs in Kenya [29].