Table 1.
Demographic and clinical variables for the FTD patients and controls, together with thalamic volumes. Values denote mean (standard deviation) or n (%).
| Groups | n | Gender, male | Age at scan (years) | Disease duration (years) | Left thalamic volume (as % of TIV) | Right thalamic volume (as % of TIV) | Total thalamic volume (as % of TIV) | |
|---|---|---|---|---|---|---|---|---|
| Controls | 99 | 42 (42%) | 61.9 (11.4) | – | 0.41 (0.03) | 0.40 (0.03) | 0.80 (0.06) | |
| Clinical | FTD-MND | 7 | 4 (57%) | 66.1 (3.8) | 4.6 (2.4) | 0.34 (0.03) | 0.35 (0.03) | 0.69 (0.06) |
| bvFTD | 141 | 41 (29%) | 61.3 (8.3) | 5.2 (3.2) | 0.37 (0.03) | 0.37 (0.02) | 0.73 (0.05) | |
| PNFA | 103 | 50 (49%) | 68.3 (8.5) | 4.3 (2.2) | 0.36 (0.03) | 0.38 (0.03) | 0.74 (0.06) | |
| PPA-NOS | 14 | 10 (71%) | 63.9 (6.3) | 3.3 (1.7) | 0.36 (0.03) | 0.39 (0.03) | 0.75 (0.06) | |
| SD | 76 | 42 (55%) | 64.0 (7.4) | 4.6 (2.3) | 0.37 (0.03) | 0.40 (0.03) | 0.77 (0.05) | |
| Genetic | C9orf72 | 24 | 17 (71%) | 60.9 (6.9) | 5.6 (3.2) | 0.35 (0.03) | 0.34 (0.03) | 0.69 (0.06) |
| GRN | 15 | 7 (47%) | 62.6 (6.6) | 2.9 (2.7) | 0.36 (0.04) | 0.35 (0.02) | 0.72 (0.04) | |
| MAPT | 24 | 15 (63%) | 55.4 (5.7) | 5.7 (3.3) | 0.37 (0.04) | 0.36 (0.04) | 0.73 (0.07) | |
| Pathological | TDP-43 | 60 | 38 (63%) | 63.1 (6.9) | 4.6 (3.0) | 0.37 (0.04) | 0.35 (0.03) | 0.72 (0.06) |
| Tau | 40 | 28 (70%) | 58.5 (8.5) | 5.1 (2.8) | 0.37 (0.04) | 0.36 (0.03) | 0.73 (0.07) | |
| FUS | 3 | 2 (67%) | 43.9 (13.6) | 3.3 (2.1) | 0.39 (0.02) | 0.40 (0.04) | 0.79 (0.07) | |