Table 3.
Asymmetry values and comparisons between the different clinical, genetic and pathological subgroups for the right, left and total thalamic volume. Analyses are adjusted for age, gender, scanner type and disease duration.
| Mean (SD) |
p-value |
|||||
|---|---|---|---|---|---|---|
| Clinical diagnosis | FTD-MND | bvFTD | PNFA | PPA-NOS | SD | |
| Control | 0.015 (0.012) | 0.289 | <0.00005 | <0.00005 | <0.00005 | <0.00005 |
| FTD-MND | 0.020 (0.013) | – | 0.887 | 0.313 | 0.015 | <0.00005 |
| bvFTD | 0.028 (0.023) | – | – | 0.669 | 0.061 | <0.00005 |
| PNFA | 0.028 (0.024) | – | – | – | 0.020 | <0.00005 |
| PPA-NOS | 0.048 (0.023) | – | – | – | – | <0.00005 |
| SD | 0.042 (0.020) | – | – | – | – | – |
| Genetic diagnosis | C9orf72 | GRN | MAPT | |
|---|---|---|---|---|
| Control | 0.015 (0.012) | 0.124 | <0.00005 | <0.00005 |
| C9orf72 | 0.022 (0.017) | – | <0.00005 | 0.879 |
| GRN | 0.051 (0.036) | – | – | 0.007 |
| MAPT | 0.027 (0.017) | – | – | – |
| Pathological diagnosis | TDP-43 | Tau | FUS | |
|---|---|---|---|---|
| Control | 0.015 (0.012) | <0.00005 | <0.00005 | 0.151 |
| TDP-43 | 0.037 (0.026) | – | <0.00005 | 0.002 |
| Tau | 0.036 (0.024) | – | – | 0.117 |
| FUS | 0.025 (0.020) | – | – | – |