Table 1.

List of proteins with largest increased expression levels in CV-PTC and FV-PTC.

Largest Increase in Expression Levels in CV-PTC
UniProt ID	Protein Name	Fold Changea	FDR corrected P-valueφ
ARPC3	Actin-related protein 2/3 complex subunit 3	1,07	7,47E-05
ANXA1	Annexin A1	2,15	0,0005
WARS	Tryptophan–tRNA ligase, cytoplasmic;T1-TrpRS;T2-TrpRS	1,64	0,0003
STAT1	Signal transducer and activator of transcription 1-alpha/beta	4,00	3,16E-05
ACTR3	Actin-related protein 3	1,12	0,0002
ACTR2	Actin-related protein 2	1,08	3,29E-06
CAP1	Adenylyl cyclase-associated protein 1	0,82	1,98E-05
MVP	Major vault protein	2,68	0,0002
PLEC	Plectin	0,76	0,0004
ARPC1B	Actin-related protein 2/3 complex subunit 1B	1,39	0,0002
ARPC2	Actin-related protein 2/3 complex subunit 2	0,89	7,37E-05
TYMP	Thymidine phosphorylase	3,12	0,0002
FLNA	Filamin-A	0,68	0,0005
PSM8	Proteasome subunit beta type	1,56	0,0002
SERPINB1	Leukocyte elastase inhibitor	0,73	0,0005
CORO1A	Coronin-1A;Coronin	4,02	0,0003
RECQL	ATP-dependent DNA helicase Q1	0,98	0,0004
ANXA11	Annexin A11	0,91	3,79E-05
ARHGDIB	Rho GDP-dissociation inhibitor 2	1,48	0,0002
S100A10	Protein S100-A10	1,76	0,0005
PICALM	Phosphatidylinositol-binding clathrin assembly protein	1,40	7,44E-05
FERMT3	Fermitin family homolog 3	4,95	7,74E-05
MZB1	Marginal zone B- and B1-cell-specific protein	7,09	7,93E-05
PARP4	Poly [ADP-ribose] polymerase 4	4,78	0,0003
SAMHD1	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	1,70	0,0001

Largest Increase in Expression Levels in FV-PTC
UniProt ID	Protein Name	Fold Changea	FDR corrected P-valueφ
IQGAP2	Ras GTPase-activating-like protein IQGAP2	1,47	0,0004
PGK1	Phosphoglycerate kinase 1	0,41	0,0005

^aFold change of protein expression level (log₂).

^φp value determined from Welch’s t-test (FDR corrected P-value <0.0005).