Fig. 5.
Principle component analysis (PCA) scores plot and loadings plot based on principle component 1 and 2, with all protein abundances in the differently preserved colon biopsies from two participants as input. (a) Scores plot of colon biopsies from participant A (filled symbols) and participant B (hollow symbols) were stabilized by direct frozen (DF) ( and ), RNAlater ( and
), immediate formalin-fixed, paraffin-embedded (iFFPE) (
and
), or 30 min stored formalin-fixed, paraffin-embedded (sFFPE) (
and
) preservation protocol. (b) Loadings plot with all quantifiable proteins. Proteins with ±0.4 were analyzed (
and
) were chosen for further analysis. The gene names of the top three extreme proteins on each axis are given. (For interpretation of the references to color in the text, the reader is referred to the web version of this article.)