Fig. 1.
Clinical impact of GPR177 in gastric cancer (GC) patients. (A-D) GPR177 expression correlates with poor prognosis in human GC patients. (A and B) Correlation of GPR177 (WLS) mRNA expression with overall survival for patients (A, n = 184; B, n = 300). Solid and broken lines denote patients whose tumors expressed lower and higher levels, respectively, than the median value. (C) Micrographs of immunohistochemical staining of GPR177 in human GC tumor samples. Representative images of negative (left) and positive (right) staining. Scale bar, 100 μm. (D) Kaplan-Meier analysis of overall survival in a data set of 909 GC samples used in immunohistochemical analysis and classified as having positive (broken line) or negative (solid line) GPR177 expression.