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. 2018 Jun 1;9(3):467–479. doi: 10.14336/AD.2018.0130

Figure 3.

Figure 3.

Splenectomy immediately after ischemic stroke reduces brain infarct early after MCAO but shows no effect on long-term brain damage. Rats were subjected to 90 min of MCAO followed by immediate splenectomy. (A) Illustration of the experimental timelines. (B) Representative images of TTC-stained coronal brain sections at 3 days after 90 min MCAO. (C) Quantification of infarct areas in each slice. n=5-6 rats per group. #p<0.05 by two-way ANOVA. (D) Quantification of infract volume. n=5-6 rats per group. #p<0.05 by Student’s t-test. (E) Representative images of MAP-2-stained coronal brain sections at 28 days after MCAO. (F) Quantification of infarct volume at 28 days after MCAO. n=5-6 rats per group. Values are mean ± SEM.