Table 1.
Abbreviations | CMC/μM | EC50 ± SD/μM | ||
---|---|---|---|---|
C6 glioma | MDCK II | NIH3T3 | ||
C7-IMe·HI | 65.9 (50~80) | 2.3 ± 0.5 | 6.7 ± 0.8 | 4.7 ± 0.8 |
C7-IBn·HBr | 17.9 (10~20) | 1.0 ± 0.1 | 12.9 ± 2.1 | 2.5 ± 0.4 |
C11-IMe·HI | 8.5 (5~10) | 10.5 ± 0.3 | 8.9 ± 0.8 | 5.0 ± 0.5 |
C11-IMe·MeI | 7.9 (5~10) | 5.3 ± 0.5 | 8.4 ± 0.5 | 1.0 ± 0.2 |
C11-IBn·HBr | 2.3 (2.0~5.0) | 2.0 ± 0.1 | 16.0 ± 5.7 | 4.2 ± 0.5 |
C15-IH·NH2Cl | 4.1 (2.5~5) | 67.2 ± 3.9 | 32.2 ± 3.3 | 12.2 ± 1.7 |
C15-IMe·HI | 1.4 (1.0~5.0) | 28.1 ± 0.7 | 15.9 ± 0.5 | 7.7 ± 0.2 |
C15-IMe·MeI | 0.9 (0.7~1.0) | 16.3 ± 0.6 | 23.6 ± 1.1 | 3.5 ± 0.9 |
C15-IBn·HBr | 0.5 (0.4~1.3) | 11.3 ± 2.0 | 20.6 ± 4.2 | 8.7 ± 0.7 |