Fig. 1.

Entropy versus enthalpy plots for changes in macromolecular processes upon co-solute addition in accordance with Eq. 23. a CD/AD complexation with enthalpy and entropy change. The inset shows the different corresponding regimes on the plot, and the blue and red colors signify stabilizing and destabilizing regions, respectively. More details can be found in the main text. b Folding of a model peptide. The inset depicts the model enthalpic and entropic contributions to charged and non-charged terms of electrolytes on peptide folding. Reproduced from Sukenik et al. (2013a) with permission from the PCCP owner societies