Table 4.
Cancer-specific patient-reported outcomes by treatment group
| Endoscopy/telescopy | Endoscopy/telescopy with chemotherapy directly into the bladder | Radical cystectomy | Radiotherapy and Intravenous chemotherapy | Radiotherapy | p-value | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Not at all/somewhat | Quite a bit/very much | Not at all/somewhat | Quite a bit/very much | Not at all/somewhat | Quite a bit/very much | Not at all/somewhat | Quite a bit/very much | Not at all/somewhat | Quite a bit/very much | ||||||||||||
| N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | ||
| Physical well-being | |||||||||||||||||||||
| I have a lack of energy | 150 | 76.9 | 45 | 23.1 | 155 | 83.3 | 31 | 16.7 | 68 | 78.2 | 19 | 21.8 | 25 | 73.5 | 9 | 26.5 | 34 | 56.7 | 26 | 43.3 | χ2 = 18.4, p < 0.01 |
| Because of my physical condition, I have trouble meeting the needs of my family | 162 | 90.5 | 17 | 9.5 | 173 | 96.1 | 7 | 3.9 | 77 | 88.5 | 10 | 11.5 | 29 | 87.9 | 4 | 12.1 | 39 | 78.0 | 11 | 22.0 | χ2 = 16.7, p < 0.01 |
| I have pain | 165 | 91.2 | 16 | 8.8 | 165 | 91.7 | 15 | 8.3 | 78 | 90.7 | 8 | 9.3 | 30 | 90.9 | 3 | 9.1 | 45 | 81.8 | 10 | 18.2 | χ2 = 5.1, p = 0.280 |
| Social/family well-being | |||||||||||||||||||||
| I feel close to my friends | 72 | 42.9 | 96 | 57.1 | 51 | 30.0 | 119 | 70.0 | 23 | 27.7 | 60 | 72.3 | 16 | 47.1 | 18 | 52.9 | 23 | 45.1 | 28 | 54.9 | χ2 = 12, p = 0.017 |
| My family has accepted my illness | 36 | 20.7 | 138 | 79.3 | 21 | 11.9 | 156 | 88.1 | 6 | 7.1 | 79 | 92.9 | 5 | 14.7 | 29 | 85.3 | 6 | 10.9 | 49 | 89.1 | χ2 = 10.9, p = 0.027 |
| I am satisfied with my sex life | 60 | 60.6 | 39 | 39.4 | 68 | 59.7 | 46 | 40.3 | 44 | 88.0 | 6 | 12.0 | 11 | 64.7 | 6 | 35.3 | 17 | 73.9 | 6 | 26.1 | χ2 = 14.8, p < 0.01 |
| Emotional well-being | |||||||||||||||||||||
| I feel sad | 100 | 88.5 | 13 | 11.5 | 121 | 91.0 | 12 | 9.0 | 57 | 85.1 | 10 | 14.9 | 18 | 85.7 | 3 | 14.3 | 29 | 87.9 | 4 | 12.1 | χ2 = 1.8, p = 0.781 |
| I am satisfied with how I am coping with my illness | 44 | 34.9 | 82 | 65.1 | 30 | 21.6 | 109 | 78.4 | 15 | 20.5 | 58 | 79.5 | 5 | 21.7 | 18 | 78.3 | 11 | 29.7 | 26 | 70.3 | χ2 = 8.1, p = 0.087 |
| I feel nervous | 106 | 86.2 | 17 | 13.8 | 124 | 90.5 | 13 | 9.5 | 64 | 90.1 | 7 | 9.9 | 21 | 95.5 | 1 | 4.5 | 32 | 97.0 | 1 | 3.0 | χ2 = 4.5, p = 0.343 |
| I worry about dying | 112 | 89.6 | 13 | 10.4 | 129 | 92.1 | 11 | 7.9 | 63 | 90.0 | 7 | 10.0 | 20 | 90.9 | 2 | 9.1 | 32 | 94.1 | 2 | 5.9 | χ2 = 1, p = 0.907 |
| I worry that my condition will get worse | 166 | 86.9 | 25 | 13.1 | 163 | 87.2 | 24 | 12.8 | 75 | 86.2 | 12 | 13.8 | 21 | 63.6 | 12 | 36.4 | 47 | 83.9 | 9 | 16.1 | χ2 = 13.3, p = 0.01 |
| Functional well-being | |||||||||||||||||||||
| I am able to work (include work from home) | 63 | 35.8 | 113 | 64.2 | 47 | 26.5 | 130 | 73.5 | 31 | 36.5 | 54 | 63.5 | 11 | 36.7 | 19 | 63.3 | 28 | 58.3 | 20 | 41.7 | χ2 = 17.2, p < 0.01 |
| My work (include work at home) is fulfilling | 56 | 33.9 | 109 | 66.1 | 48 | 28.6 | 120 | 71.4 | 31 | 38.3 | 50 | 61.7 | 8 | 28.6 | 20 | 71.4 | 26 | 57.8 | 19 | 42.2 | χ2 = 14.3, p < 0.01 |
| I am able to enjoy life | 46 | 24.5 | 142 | 75.5 | 32 | 16.8 | 159 | 83.2 | 22 | 24.7 | 67 | 75.3 | 2 | 6.1 | 31 | 93.9 | 17 | 28.8 | 42 | 71.2 | χ2 = 10.7, p = 0.03 |
| I am sleeping well | 66 | 34.2 | 127 | 65.8 | 52 | 28.0 | 134 | 72.0 | 29 | 32.2 | 61 | 67.8 | 12 | 35.3 | 22 | 64.7 | 18 | 31.0 | 40 | 69.0 | χ2 = 2, p = 0.739 |
| I am enjoying the things I usually do for fun | 53 | 28.5 | 133 | 71.5 | 37 | 20.0 | 148 | 80.0 | 25 | 29.1 | 61 | 70.9 | 11 | 33.3 | 22 | 66.7 | 21 | 38.9 | 33 | 61.1 | χ2 = 9.5, p = 0.049 |
| I am content with the quality of my life right now | 52 | 27.7 | 136 | 72.3 | 34 | 17.8 | 157 | 82.2 | 28 | 32.2 | 59 | 67.8 | 10 | 30.3 | 23 | 69.7 | 16 | 28.6 | 40 | 71.4 | χ2 = 9.2, p = 0.057 |
| Bladder cancer-specific items | |||||||||||||||||||||
| I have control of my bowels | 42 | 21.6 | 152 | 78.4 | 25 | 13.0 | 167 | 87.0 | 20 | 23.0 | 67 | 77.0 | 5 | 15.1 | 28 | 84.9 | 14 | 24.1 | 44 | 75.9 | χ2 = 7.6, p = 0.107 |
| I urinate more frequently than usual | 127 | 65.5 | 67 | 34.5 | 120 | 62.8 | 71 | 37.2 | NA | NA | NA | NA | 17 | 50.0 | 17 | 50.0 | 29 | 55.8 | 23 | 44.2 | χ2 = 4, p = 0.264 |
| I have a good appetite | 43 | 21.7 | 155 | 78.3 | 25 | 13.0 | 167 | 87.0 | 19 | 22.1 | 67 | 77.9 | 4 | 11.4 | 31 | 88.6 | 14 | 23.7 | 45 | 76.3 | χ2 = 8.2, p = 0.085 |
| It burns when I urinate | 179 | 93.7 | 12 | 6.3 | 165 | 91.2 | 16 | 8.8 | NA | NA | NA | NA | 29 | 85.3 | 4 | 14.7 | 53 | 93.0 | 4 | 7.0 | χ2 = 3.1, p = 0.377 |
| I am interested in sex | 110 | 65.9 | 57 | 34.1 | 106 | 60.2 | 70 | 39.8 | 55 | 71.4 | 22 | 28.6 | 23 | 71.9 | 9 | 28.1 | 39 | 81.3 | 9 | 18.7 | χ2 = 9.1, p = 0.059 |
| (For men only) I am able to have and maintain an erection | 91 | 66.4 | 46 | 33.6 | 76 | 59.8 | 51 | 40.2 | 52 | 94.5 | 3 | 5.5 | 17 | 89.5 | 2 | 10.5 | 34 | 89.5 | 4 | 10.5 | NA |