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. 2018 May 14;118(11):1518–1528. doi: 10.1038/s41416-018-0084-z

Table 5.

Cancer-specific patient-reported outcomes by number of long-term conditions (LTCs)

No LTC 1 LTC 2 LTCs ≥3 LTCs p-value
Not at all/somewhat Quite a bit/very much Not at all/somewhat Quite a bit/very much Not at all/somewhat Quite a bit/very much Not at all/somewhat Quite a bit/very much
N % N % N % N % N % N % N % N %
Physical well-being
 I have a lack of energy 97 91.5 9 8.5 170 85.9 28 14.1 98 76.0 31 24.0 101 55.5 81 44.5 χ2 = 66, p < 0.01
 Because of my physical condition, I have trouble meeting the  needs of my family 104 98.1 2 1.9 170 91.9 15 8.1 116 94.3 7 5.7 132 80.0 33 20.0 χ2 = 29.8, p < 0.01
 I have pain 101 97.1 3 2.9 175 94.6 10 5.4 109 87.2 16 12.8 138 81.2 32 18.8 χ2 = 24.9, p < 0.01
Social/family well-being
 I feel close to my friends 26 27.4 69 72.6 64 35.4 117 64.6 46 39.3 71 60.7 66 41.0 95 59.0 χ2 = 5.3, p = 0.150
 My family has accepted my illness 14 13.6 89 86.4 25 13.8 156 86.2 20 16.3 103 83.7 18 10.8 148 89.2 χ2 = 1.8, p = 0.609
 I am satisfied with my sex life 39 56.5 30 43.5 71 61.7 44 38.3 48 75.0 16 25.0 67 76.1 21 23.9 χ2 = 10, p = 0.018
Emotional well-being
 I feel sad 70 94.6 4 5.4 128 94.1 8 5.9 74 88.1 10 11.9 86 76.1 27 23.9 χ2 = 22.9, p < 0.01
 I am satisfied with how I am coping with my illness 16 20.8 61 79.2 31 21.8 111 78.2 22 23.7 71 76.3 47 36.2 83 63.8 χ2 = 9.5, p = 0.023
 I feel nervous 73 97.3 2 2.7 133 94.3 8 5.7 84 93.3 6 6.7 95 79.2 25 20.8 χ2 = 24.9, p < 0.01
 I worry about dying 69 90.8 7 9.2 132 93.6 9 6.4 85 94.4 5 5.6 104 83.9 20 16.1 χ2 = 9.6, p = 0.023
 I worry that my condition will get worse 91 85.8 15 14.2 166 86.5 26 13.5 113 87.6 16 12.4 145 81.0 34 19.0 χ2 = 3.3, p = 0.348
Functional well-being
 I am able to work (include work at home) 18 18.0 82 82.0 38 21.3 140 78.7 53 42.7 71 57.3 87 53.7 75 46.3 χ2 = 55.6, p < 0.01
 My work (include work at home) is fulfilling 20 21.5 73 78.5 44 26.0 125 74.0 43 36.8 74 63.2 77 51.3 73 48.7 χ2 = 31.2, p < 0.01
 I am able to enjoy life 16 15.0 91 85.0 29 14.7 168 85.3 25 19.4 104 80.6 60 33.7 118 66.3 χ2 = 24.3, p < 0.01
 I am sleeping well 23 21.9 82 78.1 52 26.8 142 73.2 44 33.1 89 66.9 75 41.9 104 58.1 χ2 = 15.5, p < 0.01
 I am enjoying the things I usually do for fun 16 15.7 86 84.3 31 16.2 160 83.8 34 27.2 91 72.8 79 45.4 95 54.6 χ2 = 47.7, p < 0.01
 I am content with the quality of my life right now 22 20.4 86 79.6 28 14.6 164 85.4 38 29.9 89 70.1 67 37.4 112 62.6 χ2 = 28.2, p < 0.01
Bladder cancer-specific items
 I have control of my bowels 14 13.3 91 86.7 30 15.3 166 84.7 27 20.3 106 79.7 45 25.0 135 75.0 χ2 = 8.3, p = 0.04
 I urinate more frequently than usual 73 70.9 30 29.1 117 63.6 67 36.4 87 70.7 36 29.3 99 55.6 79 44.4 χ2 = 10, p = 0.019
 I have a good appetite 13 12.1 94 87.9 31 16.0 163 84.0 21 15.8 112 84.2 50 26.9 136 73.1 χ2 = 13, p < 0.01
 It burns when I urinate 99 98.0 2 2.0 174 92.6 14 7.4 120 94.5 7 5.5 153 89.0 19 11.0 χ2 = 8.5, p = 0.036
 I am interested in sex 52 54.2 44 45.8 98 58.0 71 42.0 82 69.5 36 30.5 130 77.8 37 22.2 χ2 = 21.8, p < 0.01
 (For men only) I am able to have and maintain an erection 42 61.8 26 38.2 87 66.4 44 33.6 75 78.1 21 21.9 107 82.9 22 17.1 χ2 = 15.1, p < 0.01