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. 2018 Jun 6;7:98. doi: 10.1038/s41426-018-0101-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a A maximum likelihood phylogenetic tree showing genomic clusters in the Shanghai dataset. The strain identifiers were “year, strain number, and compensatory mutation type”. The three genomic cluster types are illustrated with different colors, as indicated. The isolate names in gray represent the VNTR-clustered strains that were separated by WGS. Comparison of cluster sizes in C-type, M-type, and N-type clusters in the Shanghai MDR-TB dataset (b) and the Global MDR-TB dataset (c); each dot represents a genomic cluster identified by WGS