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. 2018 Jun 5;8:8569. doi: 10.1038/s41598-018-26766-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation between aging-related parameters. (A) Pearson’s correlation coefficients matrix and (B) Correlation network. (A) The matrix contains the Pearson’s correlation coefficients between smoking pack-years, pulmonary function parameters and the 15 aging-related parameters of interest. Colors indicate the direction and the strength of the correlation, with positive correlations being displayed as blue tones and negative ones as red tones. (B) The correlation network is constructed from all pairwise correlations between items in (A). Items are represented by nodes and are connected by edges. Red and blue lines represent negative and positive correlations, respectively. Line width color saturation is proportional to the strength of the correlation.