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. 2016 Oct 5;9(2):151–157. doi: 10.1007/s13239-016-0280-z

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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The effect of shear stresses on the amount of elastin in the aortic valves. The amount of elastin was reported as µg elastin per mg dried tissue from fresh tissue (FT), static control (SC) for 48 h and the mimicked physiological flow conditions for 48 h on the aortic side (AS/AF) and ventricular side (VS/VF). The median values were statistically analysed by Kruskal–Wallis test and pair-wise compared by Dunn’s test. The amount of elastin in VS/VF samples was significantly higher than SC (p value <0.01) while the amount in SC samples was significantly reduced from FT (p value <0.001), n numbers of each group were FT = 28, CS = 19, AS/AF = 8 and VS/VF = 9.