Table 3.

Multivariate analysis showed that high intratumoral CD38⁺ plasma cell populations are significantly associated with longer disease-free survival (DFS), compared to low intratumoral CD38⁺ plasma cells populations in triple negative breast cancers (TNBCs), with the median cutoff and with every 1 percent increase.

	Hazard ratio	95% confidence interval	pValue
DFS
Intratumoral CD38+ plasma cells TNBCs High vs. low	0.28	(0.11, 0.71)	0.007*
Intratumoral CD38+ plasma cells TNBCs (every 1 percent)	0.95	(0.91, 1.00)	0.031*
Overall survival (OS)
Intratumoral CD38+ plasma cells TNBCs High vs. low	0.28	(0.10, 0.82)	0.020*
Intratumoral CD38+ plasma cells TNBCs (every 1 percent)	0.96	(0.91, 1.01)	0.126

Intratumoral CD38⁺ plasma cells are associated with better OS with the median cutoff (multivariate analysis adjusted for tumor size, grade, age, and lymph node status, intratumoral CD20⁺ B cells, and CD3⁺ T cells).

*Statistically significant.