Table 5.
Multivariate analysis of expression level of IgG genes and survival outcomes in TNBC patients (after adjustment for for tumor size, grade, age and lymph node status).
| Hazard ratio | 95% confidence interval | pValue | |
|---|---|---|---|
| Disease-free survival (DFS) | |||
| IGKC (every 1 unit increase of Nanostring count) | 0.58 | (0.39, 0.88) | 0.0103* |
| IGHM (every 1 unit increase of Nanostring count) | 0.60 | (0.42, 0.86) | 0.0055* |
| IGHG1 (every 1 unit increase of Nanostring count) | 0.66 | (0.44, 0.99) | 0.0437* |
| Overall survival (OS) | |||
| IGKC (every 1 unit increase of Nanostring count) | 0.66 | (0.41, 1.06) | 0.0854 |
| IGHM (every 1 unit increase of Nanostring count) | 0.65 | (0.40, 1.04) | 0.0707 |
| IGHG1 (every 1 unit increase of Nanostring count) | 0.64 | (0.42, 0.97) | 0.0340* |
*Statistically significant.