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. 2018 May 30;9:1124. doi: 10.3389/fimmu.2018.01124

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Copyright © 2018 Zhao, Jiang, Xu, Yang, Gao, Li, Gao, Ma and Liang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Upregulated expression of Siglec-9 ligand in HBV infection and inflammatory milieu. (A) Detection of Siglec-9 ligand in liver biopsies from chronic hepatitis B (CHB) patients or normal liver tissues by immunofluorescence using Siglec-9-Fc chimera protein. (B,C) Expression of Siglec-9 ligand and hepatitis B surface antigen (HBsAg) in hepatoma cell line HLCZ01 with or without HBV infection (B), and Huh7 cells treated with 100 ng/ml IL-6 or TNF-α for 24 h (C), was evaluated by immunofluorescence staining.