Table 2.
Mean MBT participant demographic and clinical information revealed manifest subjects were significantly older than pre-manifest subjects, and stage 2 subjects were significantly older than healthy controls.
| Controls | Pre-manifest | Manifest | Stage 1 | Stage 2 | Stage 3 | Stages 4 and 5 | |
|---|---|---|---|---|---|---|---|
| N (male: female) | 21 (9:12) | 8 (6:2) | 56 (32:24) | 23 (14:9) | 17 (8:10) | 11 (7:4) | 3 (3:1) |
| Age | 45.52 (15.03) | 37.75 (6.43) | 51.21 (12.19) | 48.43 (9.01) | 56.83 (15.69) | 50.55 (10.63) | 43.75 (5.68) |
| Total motor score | 0.375 (0.52) | 35.35 (21.07) | 21.18 (12.1) | 34.17 (12.24) | 54.82 (19.23) | 75 (20.88) | |
| Total functional capacity | 12.625 (0.52) | 8.87 (3.64) | 12.09 (0.92) | 8.94 (1.16) | 4.64 (1.36) | 0.33 (0.58) | |
| Functional scale | 24.875 (0.35) | 20.04 (5.97) | 24.5 (0.74) | 20.39 (1.46) | 13.44 (4.5) | 5 (7) | |
| Independence scale | 99.375 (1.77) | 81.3 (13.77) | 91.90 (7.49) | 79.44 (6.62) | 67.22 (7.55) | 50 (28.28) | |
| CAG disease burden score | 260.71 (69.24) | 400.29 (102.44) | 373.39 (99.25) | 411.78 (117.67) | 424.73 (87.11) | 429.38 (82.18) | |
| Education level† | 3.58 (1.51) | 3.75 (0.89) | 3.53 (0.91) | 3.71 (1.06) | 3.39 (0.78) | 3.45 (0.69) | 3.33 (1.53) |
There were no significant differences between any other group for any other variable.
†
Education level was missing in n = 9 healthy controls.