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. 2018 May 30;12:149. doi: 10.3389/fncel.2018.00149

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Copyright © 2018 Hayani, Song and Dityatev.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of GABAergic transmission onto pyramidal neurons and fast-spiking interneurons 7 days (7 d) after ChABC injection. (A) Representative traces of sEPSC from CA2 pyramidal cells (upper) and FSIs (lower) in vehicle- and ChABC-injected hippocampal slices. Bar graphs of sIPSC amplitude (B), frequency (C), rise time (D) and decay time (E) of CA2 PCs and FSIs. Bars represent mean ± SEM in vehicle- (black) and ChABC-treated (white) FSIs (Vehicle, n = 9; ChABC, n = 14) and PCs (Vehicle, n = 14; ChABC, n = 10). *P < 0.05, t-test after log-transformation to normalize distributions; **P < 0.01, t-test, compared with vehicle.