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. Author manuscript; available in PMC: 2020 Oct 1.

Published in final edited form as: Cytokine. 2017 Dec 6;122:154175. doi: 10.1016/j.cyto.2017.09.031

Table 2.

RNA binding proteins and predicted effects on atherogenicity.

RNA-binding protein	Abbreviation	Effect on TNFα mRNA levels	Mechanism	Predicted Atherogenecity
Human antigen R	HuR	Increase^105,106	Stabilizes RNA^105,106	Pro-atherogenic
Tristetraprolin	TTP	Decrease¹⁰⁷	Destabilizes RNA¹⁰⁷	Anti-atherogenic
ARE/poly(U)-binding/degradation factor	AUF-1	Decrease¹⁰⁸	Destabilizes RNA¹⁰⁸	Anti-atherogenic
T-cell-restricted intracellular antigen-1	TIA-1	Decrease¹⁰⁹	Inhibits translation¹¹⁰	Anti-atherogenic
TIA-1-related protein	TIAR	Decrease¹⁰⁹	Inhibits translation¹¹⁰	Anti-atherogenic
CUG triplet repeat RNA binding protein 1	CUGBP1	Decrease¹¹³	Destabilizes RNA^113,114	Anti-atherogenic