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. Author manuscript; available in PMC: 2018 Jun 6.
Published in final edited form as: Crit Rev Immunol. 2018;38(2):145–158. doi: 10.1615/CritRevImmunol.2018024985

FIG. 1.

FIG. 1

Histological structural organization of the rat spleen. The spleen is divided into red pulp (RP) and white pulp (WP) regions. The WP are further divided into B and T lymphocyte regions including the follicles, marginal zone and periarteriole lymphatic sheath (PALS). Visible in the WP are a secondary follicle i.e., a follicle containing a germinal center. The marginal zone (MZ) forms an interface between the RP and the WP. The MZ is further separated from the follicle and PALS by the marginal sinus.