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Cross-sectional reduced gray matter volume (Top) and increased 1-year GMV loss (Bottom) in the MAPT H1H1 group. For depiction purposes, results are displayed using p < 0.05 uncorrected and minimum cluster size (k) of 500 voxels. The set of labeled clusters survived a significance of p < 0.005 uncorrected and k = 50 voxels. No significant regions of increased gray matter volume or lower GMV loss were obtained in the H1H1 group.
