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. 2018 May;8(4):410–420. doi: 10.21037/qims.2018.05.01

Table 3. Features showing statistical difference between non-responders and responders.

Feature P value Standard error 95% CI AUC Sens Spec Cut-off
F_Skewness 0.010 0.083 0.571–0.852 0.728 0.684 0.792 ≤−0.271
LoG2.5_glszm_SALGLE 0.013 0.081 0.564–0.847 0.721 0.421 0.958 ≤4.99×10−3
WHLH_F_Mean 0.013 0.081 0.564–0.847 0.721 0.684 0.791 −3.42×10−3
glcm_CS 0.037 0.086 0.527–0.819 0.686 0.421 0.958 ≤−4.547
WLLL_F_Skewness 0.037 0.087 0.527–0.819 0.686 0.736 0.667 ≤−0.087
WHLH_glszm_SAE 0.047 0.084 0.518–0.812 0.678 0.526 0.833 ≤0.401

F, first order; LoG2.5, volume preprocessed using Laplacian of Gaussian band pass filter with 2.5 filter width; GLSZM, gray-level size-zone matrix; SALGLE, small area low gray level emphasis; WHLH, volume with a wavelet high-pass filter along x-direction, a low-pass filter along y-direction and a high-pass filter along z-direction; GLCM, gray-level co-occurrence matrix; CI, confidence interval; AUC, area under the curve; Sens, Sensitivity; Spec, Specificity; Responders, patients with CR and PR; non-responders, patients with SD.