Table 1.
Gray matter correlates of single trial visual evoked potentials.
| Cluster | Peak | Peak | peak | ||||||
| Voxels | x,y,z {mm} | x,y,z {mm} | x,y,z {mm} | p(unc) | T | equivZ | |||
| MIGRAINE PATIENTS | |||||||||
| 1 | seed | Right TPJ (infero-medial)* | 112 | 42 | −57 | 28.5 | 0.0000007 | 7,06682014 | 4,82969372 |
| 2 | · | Left TPJ (superior temporal gyrus) | 265 | −42 | −52.5 | 13.5 | 0.0000189 | 5,41838455 | 4,12002826 |
| 3 | · | Right calcarine cortex | 138 | 15 | −78 | 7.5 | 0.0001098 | 4,60539389 | 3,695312 |
| 4 | Right cerebellum | 73 | 45 | −64.5 | −55.5 | 0.0001114 | 4,59864664 | 3,69154176 | |
| 5 | · | Right TPJ (supero-lateral) | 56 | 52.5 | −57 | 49.5 | 0.0001560 | 4,44605017 | 3,60512258 |
| 45 | −57 | 54 | 0.0005979 | 3,84129429 | 3,23989488 | ||||
| 57 | −57 | 40.5 | 0.0009405 | 3,63785815 | 3,10841684 | ||||
| 6 | · | Left cerebellum | 171 | −43.5 | −61.5 | −57 | 0.0001711 | 4,40432739 | 3,58110512 |
| −42 | −76.5 | −46.5 | 0.0002026 | 4,32794714 | 3,53669723 | ||||
| 7 | Right superior occipital gyrus | 52 | 22.5 | −79.5 | 45 | 0.0001832 | 4,37347031 | 3,56323348 | |
| 8 | · | Left post-central gyrus | 32 | −12 | −37.5 | 76.5 | 0.0002073 | 4,31763268 | 3,53065637 |
| 9 | · | Right middle frontal gyrus | 298 | 27 | 30 | 42 | 0.0002677 | 4,20224047 | 3,4623527 |
| 28.5 | 24 | 55.5 | 0.0004553 | 3,96353984 | 3,31676094 | ||||
| 10 | · | Right middle temporal gyrus | 47 | 69 | −46.5 | −4.5 | 0.0003112 | 4,13454056 | 3,42165515 |
| 11 | · | Left middle frontal gyrus | 38 | −28.5 | 30 | 49.5 | 0.0003691 | 4,05785036 | 3,37498704 |
| 12 | Left cuneus | 51 | −18 | −70.5 | 28.5 | 0.0003837 | 4,04041004 | 3,36428942 | |
| 13 | · | Left calcarine cortex | 29 | −15 | −76.5 | 7.5 | 0.0004090 | 4,01174641 | 3,34663897 |
| 14 | Left middle frontal gyrus | 73 | −31.5 | 30 | 34.5 | 0.0004110 | 4,00951338 | 3,34526033 | |
| HEALTHY CONTROLS | |||||||||
| 1 | Right TPJ | 51 | 42 | −55.5 | 27 | 0.0000705 | 4,80743933 | 3,80626101 | |
| 2 | Left superior frontal gyrus | 5 | −13.5 | 24 | 63 | 0.0004295 | 3,98979211 | 3,33306205 | |
| 3 | Left superior frontal gyrus | 2 | −7.5 | 40.5 | 54 | 0.0006120 | 3,83077836 | 3,23320829 | |
| 4 | Right superior frontal gyrus | 3 | 9 | 1.5 | 72 | 0.0006326 | 3,81591582 | 3,22373767 | |
| 5 | Right superior frontal gyrus | 5 | 10.5 | 6 | 70.5 | 0.0007351 | 3,7485621 | 3,18052061 | |
| 6 | Left superior frontal gyrus | 3 | −7.5 | 37.5 | 55.5 | 0.0009264 | 3,64462614 | 3,11286349 | |
Clusters of gray matter containing voxels positively correlated to mean st-VEP amplitude above a peak T = 4.0 threshold in episodic migraine patients and healthy controls. All clusters contained voxels correlated with mean st-VEP amplitude at p < 0.001 uncorrected. *p family-wise error [FWE]-corr < 0.05 at whole brain level. The 14 ROI included as seeds/sources for connectivity analysis in episodic migraineurs were generated using volumetric masks of the clusters in this table. ROI displaying significant [p false discovery rate (FDR) < 0.05] resting state functional connectivity with the seed are marked with a dot (·) in the second column. For details of connectivity analyses see Table 2, Figure 3. TPJ, temporo-parietal junction.