Table 5.

Bias-corrected relative frequencies and prevalence estimates by AMD status for two classification systems in a five-category interpretation.

	Naïve frequencies			Bias-corrected frequencies		Bias-corrected prevalencea
	Both eyes gradable n = 885	Only one eye gradable n = 155	All n = 1040	Only one eye gradable n = 155	All n = 1040	All n = 1040
Clinical Classification
No AMD, no apparent aging changes, %	25.6	38.1	27.5	27.3	25.9	24.3 [21.5; 27.1]
No AMD, normal aging changes, %	22.9	23.2	23.0	24.9	23.2	23.1 [20.2; 26.1]
Early AMD, %	26.9	23.9	26.4	27.6	27.0	27.9 [24.8; 31.1]
Intermediate AMD, %	18.2	10.3	17.0	14.4	17.6	17.4 [14.9; 19.9]
Late AMD, %	6.3	4.5	6.1	5.7	6.2	7.4 [5.4; 9.4]
Three Continent AMD Consortium Severity Scale
No AMD, %	75.7	85.2	77.1	79.9	76.3	75.5 [72.5; 78.5]
Mild early AMD, %	9.3	7.1	8.9	9.7	9.3	9.2 [7.3; 11.2]
Moderate early AMD, %	4.6	1.9	4.2	3.0	4.4	4.4 [3.1; 5.8]
Severe early AMD, %	4.1	1.3	3.7	1.8	3.7	3.6 [2.4; 5.0]
Late AMD, %	6.3	4.5	6.1	5.5	6.2	7.3 [5.4; 9.4]

Shown are naïve relative frequencies of observed AMD stages among the participants with both eyes gradable (n = 885, worse eye), among the participants with one eye gradable (n = 155), and all analyzed participants (at least one eye gradable, n = 1040, worse eye or only available eye). We also show the bias-corrected frequencies and bias-corrected prevalence estimates using predictive values (Supplementary Text 4; Supplementary Table 12). Results are shown for the Clinical Classification⁹ and the Three Continent AMD Consortium Severity Scale¹⁰ for the five-category scale. Details by sex and age-group are shown in Supplementary Tables 14 and 15.

Abbreviations: OD = right eye; OS = left eye; AMD = age-related macular degeneration;

^aPrevalence estimates standardized by five-year-age group and sex based on the weights from the Bavarian population.