Table 6.

Bias-corrected relative frequencies and prevalence estimates by AMD status for two classification systems in a three-category interpretation.

	Naïve frequencies			Bias-corrected frequencies		Bias-corrected prevalencea
	Both eyes gradable n = 885	Only one eye gradable n = 155	All n = 1040	Only one eye gradable n = 155	All n = 1040	All n = 1040
Clinical Classification
No AMD, %	48.6	61.3	50.5	52.3	49.1	47.4 [44.0; 50.7]
“Any early or intermediate” AMDb, %	45.1	34.2	43.5	41.8	44.6	45.3 [41.8; 48.7]
Late AMD, %	6.3	4.5	6.1	5.9	6.3	7.4 [5.4; 9.4]
Three Continent AMD Consortium Severity Scale
No AMD, %	75.7	85.2	77.1	79.9	76.3	75.5 [72.5; 78.5]
“Any early” AMDc, %	18.0	10.3	16.8	14.3	17.4	17.1 [14.6; 19.7]
Late AMD, %	6.3	4.5	6.1	5.7	6.2	7.3 [5.4; 9.4]

Shown are naïve relative frequencies of observed AMD stages among the participants with both eyes gradable (n = 885, worse eye), among the participants with one eye gradable (n = 155), and all analyzed participants (at least one eye gradable, n = 1040, worse eye or only available eye). We also show the bias-corrected frequencies and bias-corrected prevalence estimates using predictive values (Supplementary Text 4; Supplementary Table 13). Results are shown for the Clinical Classification⁹ and the Three Continent AMD Consortium Severity Scale¹⁰ for the three categories “no AMD”, “any early or intermediate AMD”, and “late AMD”. Details by sex and age-group are shown in Supplementary Tables 14 and 15.

Abbreviations: OD = right eye; OS = left eye; AMD = age-related macular degeneration.

^aPrevalence estimates standardized by five-year-age group and sex based on the weights from the Bavarian population.

^bFor the Clinical Classification collapsing early AMD and intermediate AMD.

^cFor the Three Continent AMD Consortium Severity Scale, collapsing mild early AMD, moderate early AMD, and severe early AMD to “any early” AMD.