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. 2018 Jun 6;8:8689. doi: 10.1038/s41598-018-26826-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Double-label immunofluorescence illustrating co-localization of CB1R-IR, NAPE-PLD-IR, and FAAH-IR with tyrosine hydroxylase (TH). Confocal micrographs of NAc co-immunolabeled for CB1R, NAPE-PLD, or FAAH (magenta), and TH (green), a specific marker for dopaminergic projections, in core and shell. Arrows point at TH-positive axons and terminals that do not express either CB1R, NAPE-PLD, or FAAH. Scale bar = 10 µm.