Table 2.
SNP | Chr | Gene | Alleles | MAF (1,000g-CHBS) | MAF (observed) | Ancestral Allele | Test for HWE (P-Value) | Crude P-value (allele) | Adjusted P-value (allele) | OR | 95% CI |
---|---|---|---|---|---|---|---|---|---|---|---|
rs10937625 | 4 | STK32B | C/T | 17% (C) | 17.9% (C) | T | 0.204 | 0.36 | 0.39 | 0.903 | (0.726,1.124) |
rs17590046 | 4 | PPARGC1A | C/T | 6.3% (C) | 9.5% (C) | T | 0.073 | 0.132 | 0.152 | 0.802 | (0.601, 1.069) |
rs12764057 | 10 | CTNNA3 | T/G | 27.2% (G) | 32.3% (G) | T | 0.056 | 0.51 | 0.54 | 1.062 | (0.888, 1.27) |
rs10822974 | 10 | CTNNA3 | A/G | 47.1% (A) | 42.3% (A) | A | 0.380 | 0.749 | 0.782 | 0.973 | (0.821, 1.152) |
rs7903491 | 10 | CTNNA3 | A/G | 43.2% (G) | 43.1% (G) | A | 0.535 | 0.622 | 0.652 | 0.958 | (0.809, 1.135) |
Chr, chromosome; CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism; MAF, Minor Allele Frequency; 1,000g-CHB,1,000g-Chinese Han Beijing.