Table 3.
SNP | Genotype | Crude P (genotype) | Adjusted P (genotype) | Model | Crude P (model) | Adjusted P (model) | OR 95% CI | |||
---|---|---|---|---|---|---|---|---|---|---|
rs10937625 | T/T = 2 | C/T = 1 | C/C = 3 | 0.666 | 0.677 | Addition | 0.405 | 0.413 | 0.701 (0.300,1.641) | |
Case | 362 (66.3%) | 164 (30%) | 20 (3.7%) | Dominant | 0.728 | 0.737 | 0.951 (0.708, 1.276) | |||
Control | 373 (67.8%) | 165 (30%) | 12 (2.2%) | Recessive | 0.372 | 0.382 | 0.692 (0.304,1.578) | |||
rs17590046 | T/T = 1 | C/T = 2 | C/C = 3 | 0.459 | 0.436 | Addition | 0.271 | 0.247 | 1.274 (0.846, 1.919) | |
Case | 455 (83.3%) | 89 (16.5%) | 2 (0.2%) | Dominant | 0.238 | 0.217 | 0.775 (0.517, 1.162) | |||
Control | 438 (79.6%) | 110 (20%) | 2 (0.4%) | Recessive | 0.556 | 0.571 | 0.499 (0.045, 5.528) | |||
rs12764057 | T/T = 2 | G/T = 1 | G/G = 3 | 0.064 | 0.065 | Addition | 0.177 | 0.185 | 0.701 (0.415,1.186) | |
Case | 250 (45.8%) | 246 (45%) | 50 (9.2%) | Dominant | 0.055 | 0.054 | 1.315 (0.996, 1.738) | |||
Control | 237 (43.1%) | 263 (47.8%) | 50 (9.1%) | Recessive | 0.450 | 0.468 | 0.830 (0.502, 1.373) | |||
rs10822974 | G/G = 1 | G/A = 2 | A/A = 3 | 0.793 | 0.811 | Addition | 0.537 | 0.549 | 1.104 (0.807, 1.511) | |
Case | 172 (31.5%) | 282 (51.7%) | 92 (16.8%) | Dominant | 0.773 | 0.806 | 0.955 (0.662, 1.378) | |||
Control | 180 (32.7%) | 278 (50.6%) | 92 (16.7%) | Recessive | 0.619 | 0.622 | 1.078 (0.800, 1.454) | |||
rs7903491 | G/G = 2 | G/A = 1 | A/A = 3 | Addition | 0.376 | 0.383 | 0.845 (0.597, 1.233) | |||
Case | 108 (19.8%) | 260 (47.6%) | 178 (32.6%) | 0.675 | 0.682 | Dominant | 0.965 | 0.964 | 1.007 (0.749, 1.353) | |
Control | 96 (17.5%) | 276 (50.2%) | 178 (32.3%) | Recessive | 0.412 | 0.419 | 0.863 (0.604, 1.233) |
CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism; model, Genetic model.