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. 2018 May 30;9:387. doi: 10.3389/fneur.2018.00387

Table 3.

Genotype distributions of included SNPs and single-nucleotide polymorphism associated with PD according to different genetic models.

SNP Genotype Crude P (genotype) Adjusted P (genotype) Model Crude P (model) Adjusted P (model) OR 95% CI
rs10937625 T/T = 2 C/T = 1 C/C = 3 0.666 0.677 Addition 0.405 0.413 0.701 (0.300,1.641)
Case 362 (66.3%) 164 (30%) 20 (3.7%) Dominant 0.728 0.737 0.951 (0.708, 1.276)
Control 373 (67.8%) 165 (30%) 12 (2.2%) Recessive 0.372 0.382 0.692 (0.304,1.578)
rs17590046 T/T = 1 C/T = 2 C/C = 3 0.459 0.436 Addition 0.271 0.247 1.274 (0.846, 1.919)
Case 455 (83.3%) 89 (16.5%) 2 (0.2%) Dominant 0.238 0.217 0.775 (0.517, 1.162)
Control 438 (79.6%) 110 (20%) 2 (0.4%) Recessive 0.556 0.571 0.499 (0.045, 5.528)
rs12764057 T/T = 2 G/T = 1 G/G = 3 0.064 0.065 Addition 0.177 0.185 0.701 (0.415,1.186)
Case 250 (45.8%) 246 (45%) 50 (9.2%) Dominant 0.055 0.054 1.315 (0.996, 1.738)
Control 237 (43.1%) 263 (47.8%) 50 (9.1%) Recessive 0.450 0.468 0.830 (0.502, 1.373)
rs10822974 G/G = 1 G/A = 2 A/A = 3 0.793 0.811 Addition 0.537 0.549 1.104 (0.807, 1.511)
Case 172 (31.5%) 282 (51.7%) 92 (16.8%) Dominant 0.773 0.806 0.955 (0.662, 1.378)
Control 180 (32.7%) 278 (50.6%) 92 (16.7%) Recessive 0.619 0.622 1.078 (0.800, 1.454)
rs7903491 G/G = 2 G/A = 1 A/A = 3 Addition 0.376 0.383 0.845 (0.597, 1.233)
Case 108 (19.8%) 260 (47.6%) 178 (32.6%) 0.675 0.682 Dominant 0.965 0.964 1.007 (0.749, 1.353)
Control 96 (17.5%) 276 (50.2%) 178 (32.3%) Recessive 0.412 0.419 0.863 (0.604, 1.233)

CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism; model, Genetic model.