Table 2.

The baseline characteristics of patient group

Nr.	Probands age at diagnosis (years)	Primary cancer site	Morphological subtype	Breast cancersubtype	Tumor grade	Family history
1	54	Breast	Ductal	Luminal	missing	Mother and maternal aunt – breast cancer age 60; daughter - polycytemia vera age15, brother – melanoma age 60
2	40	Breast	Ductal	Triple-negative*	G3	Mother - Breast and ovarian cancer age 40
3	33 and 38	Left Breast/ Right Breast	Ductal/ Ductal	Triple-negative/ Luminal	G3/G3	Paternal grandmother - unknown primary gynecological cancer age 50
4	63	Breast and Ovaries	Ductal	Triple-negative	G2	Mother with breast cancer age 55; sister - ovarian cancer age 59
5	37	Ovaries	NA	NA	NA	Mother - breast cancer age 64
6	58	Breast	Lobular	Luminal	G2	Mother and maternal aunt – breast cancer age > 60
7	43	Breast	Ductal	Triple-negative	G3	No
8	42	Breast	Ductal/Medullary	Triple-negative	G2	Mother - breast cancer age 60
9	50	Breast	Ductal	Triple-negative	G3	Mother - breast cancer age 52
10	35	Breast	Ductal	Triple-negative	G3	Mother - breast cancer age 46
11	52	Breast	Ductal	Luminal B HER2 positive	G2	Mother and maternal aunt – breast cancer age > 50
12	41	Breast	Ductal	HER2 positive	G3	No
13	53	Breast	Ductal	Triple-negative	missing	No
14	36	Breast	Ductal	Luminal	missing	No
15	53	Breast	Ductal	Luminal	missing	Mother and maternal grandmother – breast cancer age > 60 years
16	40	Breast	Ductal	Luminal B HER2 positive	missing	No