Table 3.

Drug-pathway association in the DTPN of HER2 subtype

Drug	Pathway	nNE and PCI (vs NE = 0.3492)
Fluoracil	Salvage pathways of pyrimidine deoxyribonucleotides	0.3482 (PCI 0.27%)
Docetaxel	Epithelial adherens junction signaling	0.3485 (PCI 0.17%)
Fulvestrant	Bladder cancer signaling	0.3473 (PCI 0.51%)
Methotrexate	Salvage pathways of pyrimidine deoxyribonucleotides	0.3482 (PCI 0.27%)
Tamoxifen	Human embryonic stem cell pluripotency (1); regulation of the epithelial-mesenchymal transition (2)	(1) 0.3464 (PCI 0.78%) (2) 0.3490 (PCI 0.02%) (1–2) 0.3462 (PCI 0.84%)