Fig. 3.

Performance comparison of our proposed method and existing network-based methods, evaluated by CGC list [45]. The precision recall curves of the results of our proposed method (red), DawnRank (brown), DriverNet (medium purple), HotNet2 (orange), ReMIC(β=0.01) (green), ReMIC(β=0.02) (cyan), ReMIC(β=0.03) (blue), MUFFINN(DNmax) (violet), MUFFINN(DNsum) (magenta) and baseline by mutation frequency (gray), for datatsets of (a) GBM, (b) COADREAD and (c) BRCA. The AUCs of precision recall curves of the competing methods, displayed as bar plot, for datatsets of (d) GBM, (e) COADREAD and (f) BRCA. The black dash lines in (d)–(f) represent the AUC values of baseline by mutation frequency