Table 1.
Fisher’s exact test on the top scored candidates of COADREAD results for CGC and IntOGen benchmarking genes
| CGC | IntOGen | |||||||
|---|---|---|---|---|---|---|---|---|
| Top | 50 | 100 | 150 | 200 | 50 | 100 | 150 | 200 |
| Proposed | 3.05e-12 | 9.59e-16 | 9.86e-18 | 3.35e-16 | 1.66e-15 | 2.48e-17 | 1.88e-18 | 1.30e-18 |
| HotNet2 | 9.07e-02 | 1.74e-01 | 2.49e-01 | 5.46e-02 | 5.51e-02 | 1.76e-01 | 3.15e-01 | 1.94e-01 |
| ReMIC(β = 0.01) | 9.07e-02 | 1.52e-02 | 2.74e-03 | 3.06e-05 | 8.78e-08 | 4.77e-13 | 3.45e-13 | 7.59e-15 |
| ReMIC(β = 0.02) | 9.07e-02 | 1.52e-02 | 2.74e-03 | 4.97e-04 | 8.78e-08 | 4.77e-13 | 3.45e-13 | 7.59e-15 |
| ReMIC(β = 0.03) | 3.99e-03 | 8.54e-04 | 1.66e-04 | 4.97e-04 | 1.96e-06 | 2.11e-10 | 3.45e-13 | 1.72e-12 |
| MUFFINN(DNmax) | 1.00e-00 | 1.00e-00 | 1.00e-00 | 1.00e-00 | 1.00e-00 | 1.00e-00 | 1.00e-00 | 1.00e-00 |
| MUFFINN(DNmax) | 1.00e-00 | 1.00e-00 | 1.00e-00 | 1.00e-00 | 1.00e-00 | 1.00e-00 | 6.32e-01 | 4.09e-01 |
The p-values are for the results our proposed method, HotNet2, ReMIC(β=0.01), ReMIC(β=0.02), ReMIC(β=0.03), MUFFINN(DNmax) and MUFFINN(DNsum)